GHK-Cu
COA published
A copper-binding tripeptide complex investigated in dermal-matrix and wound-research models.
From$38.00Select size
KPV
CAS67727-97-3MEASURED PURITY99.79%
An alpha-MSH tripeptide fragment investigated in inflammatory-pathway research.
- Test methods
- HPLC-UV + LC-MS
- Purity target
- 99%+ verified
- Sizes available
- 2
- Availability
- In stock
Select size
Quantity
1
Total
$49.00
That's the price. No inflated list, no permanent “discount” code to make it look cheaper than it is.
Batch J_0726-01-KPV10 · Certificate of Analysis available
For Research Use Only. Not for Human Consumption.
Products supplied by Synthrex Biotech LLC are intended strictly for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics, or dietary supplements, and are not approved by the FDA for human or veterinary use. They are not sold for, and must not be used for, human or animal consumption or administration of any kind. Synthrex Biotech LLC is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, and is not an outsourcing facility as defined under section 503B of that Act. By purchasing, you affirm that you are a qualified researcher acquiring these materials for lawful research purposes only. A Safety Data Sheet (SDS/MSDS) is available on request for every compound.
Sold by Synthrex Biotech LLC. A Safety Data Sheet (SDS) is available on request at support@synthrexbiotech.com.
✦ Research Notes
Background & literature
Origin
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone — residues 11 to 13, lysine-proline-valine. Its interest to researchers comes from a specific structural observation: the tripeptide retains a portion of α-MSH’s activity in inflammation models while lacking the melanocortin-receptor pigmentation activity of the full 13-residue hormone. That dissociation — keeping one property while dropping another — is why the fragment was pursued rather than the parent.
What has been characterised
Characterised in murine and keratinocyte models as a melanocortin-derived tripeptide with described activity on NF-κB signalling. Published work has examined KPV in murine models of inflammatory bowel disease and studied α-MSH, MSH(11–13) KPV and ACTH signalling in human keratinocyte cells in vitro. There is also literature on transport of the tripeptide by PepT1. Animal and cell-culture work throughout. Not FDA-approved for any use.
Sources
- 1.Inflamm Bowel Dis, 2008. PMID 18092346 — NF-κB signalling in murine gastrointestinal models (title not reproduced here)
- 2.“alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells.” J Invest Dermatol, 2004. PMID 15102092
These notes are provided for scientific context only. They describe published laboratory and preclinical research and are not a claim of any effect in humans. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Batch releases & restocks
Know when the next batch is tested
We publish an independent certificate for every lot before it ships. Join the Lab List and we'll tell you when a new one lands and when a sold-out compound is back — plus 15% off your first order, shown on screen the second you join.
Batch and restock notices from Synthrex Biotech LLC. No dosing advice, ever. One-click unsubscribe on every email.
Related Compounds
Snap-8
An octapeptide studied in SNARE-complex and neuromuscular-signalling research.
From$38.00Notify me
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.