MOTS-c
A mitochondrial-derived peptide studied in metabolic-signalling and cellular-energetics research.
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Epithalon
CAS307297-39-8MEASURED PURITY99.37%
A synthetic tetrapeptide studied in telomere-biology and cellular-senescence research.
- Test methods
- HPLC-UV + LC-MS
- Purity target
- 99%+ verified
- Sizes available
- 3
- Availability
- In stock
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Quantity
1
Total
$52.00
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Batch SYX-EPI50-0726 · Certificate of Analysis available
For Research Use Only. Not for Human Consumption.
Products supplied by Synthrex Biotech LLC are intended strictly for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics, or dietary supplements, and are not approved by the FDA for human or veterinary use. They are not sold for, and must not be used for, human or animal consumption or administration of any kind. Synthrex Biotech LLC is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, and is not an outsourcing facility as defined under section 503B of that Act. By purchasing, you affirm that you are a qualified researcher acquiring these materials for lawful research purposes only. A Safety Data Sheet (SDS/MSDS) is available on request for every compound.
Sold by Synthrex Biotech LLC. A Safety Data Sheet (SDS) is available on request at support@synthrexbiotech.com.
✦ Research Notes
Background & literature
Origin
Epithalon (also written epitalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, developed by Vladimir Khavinson at the St Petersburg Institute of Bioregulation and Gerontology. It is the synthetic counterpart of epithalamin, a polypeptide extract of the pineal gland that Khavinson’s group worked on from the 1970s. It belongs to the broader Russian “peptide bioregulator” programme — short peptides proposed to act at the level of gene expression, a research tradition largely conducted within Russian institutions and, for most of its history, published in Russian-language journals.
What has been characterised
The published mechanism claim is that short peptides of this type interact with DNA and influence gene expression, with the specific proposal that epithalon affects telomerase expression in cell culture. A 2025 review in the International Journal of Molecular Sciences provides the most accessible English-language overview of the compound and its reported properties. Read that literature knowing its provenance: much of the primary work originates from a single research group, and independent replication outside that programme is limited. Not FDA-approved for any use.
Sources
- 1.“Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties.” Int J Mol Sci, 2025. PMID 40141333
- 2.“Short Peptides Regulate Gene Expression.” Bull Exp Biol Med, 2016. PMID 27909961
These notes are provided for scientific context only. They describe published laboratory and preclinical research and are not a claim of any effect in humans. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Related Compounds
NAD+
COA published
A coenzyme studied in cellular-energetics, redox-balance and sirtuin-pathway research.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.