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Tesamorelin research vial — for laboratory research use only
Growth Hormone

Tesamorelin

CAS218949-48-5MEASURED PURITY99.57%

A growth-hormone-releasing factor analog examined in endocrine-pathway research models.

Test methods
HPLC-UV + LC-MS
Purity target
99%+ verified
Sizes available
2
Availability
In stock

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Quantity

1

Total

$52.00

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Batch J_0726-01-TES10 · Certificate of Analysis available

For Research Use Only. Not for Human Consumption.

Products supplied by Synthrex Biotech LLC are intended strictly for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics, or dietary supplements, and are not approved by the FDA for human or veterinary use. They are not sold for, and must not be used for, human or animal consumption or administration of any kind. Synthrex Biotech LLC is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, and is not an outsourcing facility as defined under section 503B of that Act. By purchasing, you affirm that you are a qualified researcher acquiring these materials for lawful research purposes only. A Safety Data Sheet (SDS/MSDS) is available on request for every compound.

Sold by Synthrex Biotech LLC. A Safety Data Sheet (SDS) is available on request at support@synthrexbiotech.com.

✦ Research Notes

Background & literature

Origin

Tesamorelin is a synthetic analog of growth-hormone-releasing factor, structurally GHRH(1–44) with a trans-3-hexenoyl group attached at the N-terminus. That modification protects the peptide from dipeptidyl peptidase-4 cleavage, the enzymatic step that limits native GHRH. It was developed by Theratechnologies, reviewed as an investigational drug in 2009, and is one of very few compounds in this catalog with an approved human indication — it was reviewed by the FDA and authorised in 2010 for a narrow, specific use. The material supplied here is a research chemical, not that approved product.

What has been characterised

Characterised as a GHRH-receptor agonist at the anterior pituitary. Its distinguishing structural feature is N-terminal modification conferring resistance to DPP-4 degradation, which is what separates it pharmacologically from unmodified GHRH(1–44). The material supplied here is a research chemical and is not the approved pharmaceutical product, is not prescribed, and carries no approved indication in this form. GHRH analogs appear on the WADA Prohibited List.

Sources

  1. 1.“Tesamorelin, a human growth hormone releasing factor analogue.” Expert Opin Investig Drugs, 2009. PMID 19243281
  2. 2.Ann Pharmacother, 2012. PMID 22298602 — a pharmacology review of the GHRH analogue (title not reproduced here)

These notes are provided for scientific context only. They describe published laboratory and preclinical research and are not a claim of any effect in humans. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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