PT-141 (Bremelanotide)
A melanocortin-receptor agonist studied in central nervous system pathway research.
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Melanocortin Receptor Peptides
The melanocortin system runs on five receptors, MC1R through MC5R, and this class exists because a single research programme at the University of Arizona in the 1980s set out to make a stable analogue of alpha-MSH and ended up producing several. Melanotan I (afamelanotide) is the linear analogue; Melanotan II is the cyclic one, and it is more potent but far less selective across the receptor subtypes. PT-141 (bremelanotide) exists because of an unplanned observation during Melanotan II testing — effects unrelated to pigmentation — and was developed from that lead as a metabolite. Kisspeptin-10 is the outlier: it acts at GPR54, not a melanocortin receptor, and is included here because its literature sits alongside the others in neuroendocrine signalling work. All characterisation is rodent and in-vitro.
4 compounds · For Research Use Only. Not for Human Consumption.
4 of 4 products
Kisspeptin-10
A KISS1-derived peptide investigated in reproductive-axis signalling research.
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Melanotan I
A melanocortin analog studied in receptor-binding and pigmentation-pathway research.
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Melanotan II
A melanocortin-receptor agonist analog studied in receptor-binding research.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.